Site of DNA cleavage - Recombination Signal Sequence (RSS) 

TLS Online TPP Program

#Id: 6872

#Unit 3. Fundamental Processes

RNA-induced silencing complex (RISC/RITS) remodeling complexes to chromatin to form heterochromatin in telomeres.

The siRNA complex promotes methylation of histone H3K9 by the Clr4 methyltransferase (also known as KMT1, a homolog of Drosophila Su[Var]3–9). H3K9 methylation recruits the S. pombe homolog of HP1, Swi6.

TLS Online TPP Program

#Id: 1512

#Unit 2. Cellular Organization

In a microtubule,

The end with exposed β-subunits is the (+) end

The end with exposed α-subunits is the (−) end

 

TLS Online TPP Program

#Id: 4457

#Unit 13. Methods in Biology

Scanning electron microscopy (SEM) allows investigators to view the surfaces of unsectioned metal-coated specimens

TLS Online TPP Program

#Id: 4020

#Unit 2. Cellular Organization

Local genome alteration, termed kataegis involves activation-induced deaminase (AID)

Chromothripsis entire chromosomes or large parts thereof are shattered (thripsis in Greek means “shattering”) and stitched together again in what appears to be a random manner, leading to dozens or sometimes even hundreds of rearrangements.

TLS Online TPP Program

#Id: 7694

#Unit 1. Molecules and their Interaction Relevant to Biology

                                                        aa motif / Coiled-coils

3.6 a.a / turn in helix 

abcdefg 'a' &'d’ are hydrophobic residues 'e' and 'g' are found to be charged amino 

7.2 a.a / 2 turns acids 

 —7 amino acids per 2 turns in the helix 

For every turn there could be one hydrophobic residue coming same side of the helix 

Ex: GCN4