The biosynthesis of gibberellins is under strict genetic, developmental, and environmental control, and numerous gibberellin-deficient mutants have been isolated.  Mendel’s tall/dwarf alleles in peas are a famous example. Such mutants have been useful in elucidating the complex pathways of gibberellin biosynthesis.

TLS Online TPP Program

#Id: 6153

#Unit 3. Fundamental Processes

DinB and UmuC are members of a distinct family of DNA polymerases found in many organisms known as the Y family of DNA polymerases. There are five translesion polymerases known in humans, four of which belong to the Y family. 

TLS Online TPP Program

#Id: 6154

#Unit 3. Fundamental Processes

These polymerases are template-dependent, they incorporate nucleotides in a manner that is independent of base pairing.

TLS Online TPP Program

#Id: 6155

#Unit 3. Fundamental Processes

Human member of the Y family of translesion polymerases (DNA Pol n) correctly inserts two A residues opposite a thymine dimer. 

TLS Online TPP Program

#Id: 6156

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 6157

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 6158

#Unit 3. Fundamental Processes