In healthy mitochondria, PINK1 resides in the mitochondrial matrix.

In damaged or dysfunctional mitochondria, PINK1 resides on the outer mitochondrial membrane, where it recruits cytosolic Parkin.

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#Unit 13. Methods in Biology

The TUNEL Assay measures Apoptotically Generated DNA Fragmentation.

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#Unit 4. Cell Communication and Cell Signaling

Integrins function as adhesion receptors and CAMs in wide variety of epithelial and nonepithelial cells, mediating cell-matrix and cell-cell interactions.

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#Unit 4. Cell Communication and Cell Signaling

In resting cells,

NF-κB binds directly to an inhibitor called I-κBα

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#Id: 6654

#Unit 3. Fundamental Processes

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#Id: 2450

#Unit 3. Fundamental Processes

The lac operator overlaps the promoter, and so the repressor bound to the operator physically prevents RNA polymerase from binding to the promoter and thus initiating RNA synthesis.