The SRP is made up of six proteins bound to a 300-nucleotide RNA, which acts as a scaffold for the hexamer.

TLS Online TPP Program

#Id: 4916

#Unit 1. Molecules and their Interaction Relevant to Biology

Lineweaver-Burk plot showing the effect of competitive inhibition; (b) the same, showing plots for several inhibitor concentrations at fixed enzyme concentrations.

TLS Online TPP Program

#Id: 4919

#Unit 1. Molecules and their Interaction Relevant to Biology

Secondary plots for competitive inhibition.

TLS Online TPP Program

#Id: 4922

#Unit 1. Molecules and their Interaction Relevant to Biology

Therefore, at fixed [S0], a plot of 1/v0 against [Io] (the Dixon plot) is linear. When [Io] = -Ki , it can be seen that 1/v0 = l!V max and is therefore independent of [S0], so Dixon plots for different values of [So] (but fixed [Eo]) intersect where [lo] = -Ki

TLS Online TPP Program

#Id: 4924

#Unit 1. Molecules and their Interaction Relevant to Biology

TLS Online TPP Program

#Id: 4929

#Unit 1. Molecules and their Interaction Relevant to Biology

Lineweaver-Burk plot showing the effect of uncompetitive inhibition; (b) the same, showing plots for several inhibitor concentrations at fixed enzyme concentration.

TLS Online TPP Program

#Id: 4931

#Unit 1. Molecules and their Interaction Relevant to Biology

Non-competitive inhibition