Membranes of late endosomes and lysosomes contain V-class proton pumps that act in concert with Cl- channels to acidify the vesicle lumen.

TLS Online TPP Program

#Id: 8773

#Unit 1. Molecules and their Interaction Relevant to Biology

Techniques for Measuring Stability

Absorbance (e.g. Trp, Tyr) 

Fluorescence (Trp)-difference in emission max & intensity.

CD (far or near UV) - (2o or 3o) 

NMR 

DSC (calorimetry) 

Urea gradient gels - difference in the migrating rates between F and U.

Catalytic activity 

Chromophoric or fluorophoric probes/FRET 

TLS Online TPP Program

#Id: 7288

#Unit 6. System Physiology – Plant

TLS Online TPP Program

#Id: 1895

#Unit 4. Cell Communication and Cell Signaling

T-Cell Activation and Differentiation

TLS Online TPP Program

#Id: 9609

#Unit 4. Cell Communication and Cell Signaling

Phosphorylation leads to a conformational change in the activation loop that unblocks kinase active site by reducing the Kd for ATP or the substrate to be phosphorylated.

TLS Online TPP Program

#Id: 7201

#Unit 5. Developmental Biology

MHC molecules in mouse