Membranes of late endosomes and lysosomes contain V-class proton pumps that act in concert with Cl- channels to acidify the vesicle lumen.

TLS Online TPP Program

#Id: 3601

#Unit 3. Fundamental Processes

In most cases, codons that specify the same amino acid differ only at the third base.

TLS Online TPP Program

#Id: 3603

#Unit 3. Fundamental Processes

All the codons will be formed with equal frequency if the ratio of A:T:G:C is 1:1:1:1 concentration in the cell.

TLS Online TPP Program

#Id: 3604

#Unit 3. Fundamental Processes

The translation machinery is composed of four primary components: mRNAs, tRNAs, aminoacyl-tRNA synthetases, and the ribosome.

TLS Online TPP Program

#Id: 3605

#Unit 3. Fundamental Processes

There are two major steps to start translation

1. Activation of amino acids,

2. Assembly of ribosomes.

TLS Online TPP Program

#Id: 3607

#Unit 3. Fundamental Processes

The tRNAs provide the physical interface between the amino acids being added to the growing polypeptide chain and the codons in the mRNA.

TLS Online TPP Program

#Id: 3608

#Unit 3. Fundamental Processes

Aminoacyl-tRNA synthetases couple amino acids to specific tRNAs that recognize the appropriate codon(s).