Irreversible inhibitors, such as the organophosphorus and organomercury compounds, cyanide, carbon monoxide and hydrogen sulphide, combine with the enzyme to form a covalent bond. 

TLS Online TPP Program

#Id: 6000

#Unit 3. Fundamental Processes

The origin recognition complex (ORC) is a highly conserved complex found in all eukaryotes.  It is composed of six proteins with a mass of 400 kD.  ORC binds to the yeast A and B1 elements on the A-T–rich strand and is associated with ARS elements throughout the cell cycle.

TLS Online TPP Program

#Id: 9352

#Unit 4. Cell Communication and Cell Signaling

RIII, also called β-glycan, is a cell-surface proteoglycan.

TLS Online TPP Program

#Id: 6465

#Unit 3. Fundamental Processes

Proteins bound at enhancer elements interact with proteins bound at promoter elements via DNA looping, very often through intermediates called coactivators.

TLS Online TPP Program

#Id: 10055

#Unit 4. Cell Communication and Cell Signaling

Growth factors and EGFs are synthesized as TM proteins, regulated cleavage of the precursor by members of the ADAM protease releases the active molecule into the extracellular space.

TLS Online TPP Program

#Id: 7013

#Unit 5. Developmental Biology

All tissue types possess a unique stem cell niche, and despite many differences among the niche architecture of different tissues.