Some thermostable proteins are stabilized by an increased size of the protein’s hydrophobic core, an increased size of the interface between its domains and/or subunits, and a more tightly packed core as evidenced by a reduced surface-to-volume ratio.

TLS Online TPP Program

#Id: 1518

#Unit 2. Cellular Organization

In MTOCs, 

The (−) end of the microtubule stays anchored in the MTOC while the (+) end extends away from it.

TLS Online TPP Program

#Id: 1519

#Unit 2. Cellular Organization

In cilia and flagella,

microtubules are assembled from an MTOC called a basal body.

TLS Online TPP Program

#Id: 1520

#Unit 2. Cellular Organization

Two different types of microtubule structures can exist, 

one in the T form bound to GTP 

one in the D form bound to GD

TLS Online TPP Program

#Id: 1521

#Unit 2. Cellular Organization

Free-energy change for dissociation of a subunit from the D-form polymer is more favorable (negative) than the free-energy change for dissociation of a subunit from the T-form polymer.

TLS Online TPP Program

#Id: 1522

#Unit 2. Cellular Organization

Hard keratins make up hair and nails. These keratins are rich in cysteine residues that become oxidized to form disulfide bridges, thereby strengthening the proteins.

TLS Online TPP Program

#Id: 1523

#Unit 2. Cellular Organization

Primary building block of intermediate filaments is a dimer held together through the rod domains, which associate as a coiled coil.