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TLS Online TPP Program

#Id: 8851

Geminin is expressed in late G1; it binds to and inhibits Cdt1 preventing reloading of the MCM helicase.

#Unit 2. Cellular Organization #Steps in cell cycle, regulation and control of cell cycle #Part B Pointers
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TLS Online TPP Program

#Id: 6917

#Unit 8. Inheritance Biology

Unbalanced gene dosage leads to developmental abnormalities.
TLS Online TPP Program

#Id: 6918

#Unit 8. Inheritance Biology

Chromosome deletion 
TLS Online TPP Program

#Id: 6919

#Unit 8. Inheritance Biology

Chromosome deletion - Loss of a chromosome segment.
TLS Online TPP Program

#Id: 6920

#Unit 8. Inheritance Biology

Deletion include,
Terminal deletion
ntercalary/interstitial deletion 
Microdeletion
TLS Online TPP Program

#Id: 6921

#Unit 8. Inheritance Biology

Cri-du- chat syndrome- Deletion on 5, short arm
Wolf– Hirschhorn syndrome- Deletion on 4, short arm
Williams– Beuren syndrome - Deletion on 7, long arm
Prader– Willi syndrome- Deletion on 15 long arm 
TLS Online TPP Program

#Id: 6922

#Unit 8. Inheritance Biology

Deletion of a number of pairs that is not evenly divisible by three will lead to a frameshift mutation.