The entire process of mitotic CDKs activation and entry into mitosis involves two positive feedback loops and coordination between events at the centrosome, in the cytoplasm, and in the nucleus.

TLS Online TPP Program

#Id: 2833

#Unit 13. Methods in Biology

The peptide or protein (known as a ‘ tag’) can be placed at the N- or C-terminal ends and provides a means for the fusion protein to be selectively purified from the cell extract by affinity chromatography.

TLS Online TPP Program

#Id: 8221

#Unit 2. Cellular Organization

The M6P receptor protein binds to M6P at pH 6.5–6.7 in the TGN lumen and releases it at pH 6, in the lumen of endosomes.

TLS Online TPP Program

#Id: 9925

#Unit 4. Cell Communication and Cell Signaling

Adenoviruses and cytomegalo virus use to reduce the surface expression of class I MHC molecules, 

Measles virus and HIV, reduce levels of class II MHC molecules on the surface, 

Vaccinia virus, secreting a protein that binds to the C4b complement component.

TLS Online TPP Program

#Id: 7912

#Unit 2. Cellular Organization

The majority of proteins located in mitochondria are not encoded by mtDNA, they are encoded by genes in the nucleus and are imported into the mitochondria after their synthesis in the cytosol.

TLS Online TPP Program

#Id: 3527

#Unit 2. Cellular Organization

RFLPs and SNPs can be the basis for linkage maps and are useful for establishing parent–offspring relationships.