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TLS Online TPP Program

#Id: 8961

No matter how it is born, a new gene starts its life as a single copy in the population.

As with any new mutation, by far the most likely outcome is that it will be lost by random drift or selection over the next few generations

#Unit 11. Evolution and Behavior #Origin of new genes and proteins #Part B Pointers
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TLS Online TPP Program

#Id: 8605

#Unit 2. Cellular Organization

S phase Cyclin–CDKs
In human - cyclin A-CDK 2 
In budding yeast - CIb 5/6-Cdc 28
TLS Online TPP Program

#Id: 8606

#Unit 2. Cellular Organization

M phase Cyclin–CDKs
In human - cyclin A-CDK 1
cyclin B-CDK 1
In budding yeast - CIb 1/2/3/4-Cdc 28
TLS Online TPP Program

#Id: 8607

#Unit 2. Cellular Organization

Cdk1 
=Cdc2 (vertebrates and fission yeast)
= Cdc28  (budding yeast)
TLS Online TPP Program

#Id: 8608

#Unit 2. Cellular Organization

There are three D cyclins in mammals:
cyclins D1, D2, and D3
TLS Online TPP Program

#Id: 8609

#Unit 2. Cellular Organization

In free CDK2, the A-loop blocks access of protein substrates to the γ phosphate of the bound ATP.
TLS Online TPP Program

#Id: 8610

#Unit 2. Cellular Organization