Binding of cAMP by an R subunit of PKA occurs in a cooperative fashion; i.e., binding of the first cAMP molecule to CNB-B lowers the Kd for binding of the second cAMP to CNB-A.

TLS Online TPP Program

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#Unit 3. Fundamental Processes

In C. elegans, about 70% of genes are processed by the trans-splicing mechanism

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#Unit 3. Fundamental Processes

A very different form of RNA editing is found in the RNA transcripts that encode proteins in the mitochondria of trypanosomes.

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#Unit 3. Fundamental Processes

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#Unit 3. Fundamental Processes

Editing involves the transfer of Us into the gap in the message.This process is catalyzed by the enzyme 3’ terminal uridylyl transferase (TUTase).

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#Unit 3. Fundamental Processes

Deamination of the human apolipoprotein B mRNA takes place by an enzyme called APOBEC1

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#Unit 3. Fundamental Processes

APOBEC3G (A3G)—is a potent inhibitor of infection by a range of retroviruses, including HIV. deaminates Cs to produce Us in that DNA strand, leading to hypermutation at levels the virus cannot accommodate, or even to destruction of the damaged strand by DNA glycosylase and apurinic apyrimidinic endonuclease