N2 constitutes about 80% of the earth’s atmosphere, but the stability of its triple bond renders it inert and metabolically inaccessible to most organisms.

TLS Online TPP Program

#Id: 8269

#Unit 1. Molecules and their Interaction Relevant to Biology

Nitrogenous Base pairs & aromatic amino acids stack together through pi, pi-electronic interactions. These stacking interactions are best example of VWI.

TLS Online TPP Program

#Id: 8270

#Unit 1. Molecules and their Interaction Relevant to Biology

TLS Online TPP Program

#Id: 8271

#Unit 1. Molecules and their Interaction Relevant to Biology

Misplaced Dispersion forces are responsible for

1. Sickle-Cell Anemia

2. Alzheimer's disease

3. CFTR

4. Huntington disease

TLS Online TPP Program

#Id: 8272

#Unit 1. Molecules and their Interaction Relevant to Biology

A hydrogen bond is an intermolecular force (IMF) that forms a special type of dipole-dipole attraction when a hydrogen atom bonded to a strongly electronegative atom exists in the vicinity of another electronegative atom with a lone pair of electrons.

TLS Online TPP Program

#Id: 8273

#Unit 1. Molecules and their Interaction Relevant to Biology

Hydrogen bonds are generally stronger than ordinary dipole-dipole and dispersion forces, but weaker than true covalent and ionic bonds.

TLS Online TPP Program

#Id: 8274

#Unit 1. Molecules and their Interaction Relevant to Biology

Two Requirements for Hydrogen Bonding:

First molecules has hydrogen attached to a highly electronegative atom (N, O, F) called as (hydrogen bond donor)

Second molecule has a lone pair of electrons on a small highly electronegative atom (N, O, F) called as (hydrogen bond acceptor)