Simultaneously, two serines in each Smad2/3 phosphorylated by RI receptor kinase bind to phosphoserine-binding sites in the MH2 domains of a Smad4

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#Id: 8895

#Unit 2. Cellular Organization

Monotelic attachment 

only one kinetochore can attach to microtubules

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#Id: 1492

#Unit 4. Cell Communication and Cell Signaling

MDM2 transcription is increased by p53. 

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#Id: 7480

#Unit 4. Cell Communication and Cell Signaling

IgA is the principal class in secretions, the most important being those from the epithelia lining the intestinal and respiratory tracts.

Dimeric IgA operates mainly on epithelial surfaces.

This monomeric IgA is predominantly of the subclass IgA1; the ratio of IgA1 to IgA2 in the blood is 10:1.

IgA antibodies produced by plasma cells in the gut are dimeric and predominantly of subclass IgA2; the ratio of IgA2 to IgA1 in the gut is 3:2.

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#Id: 3044

#Unit 3. Fundamental Processes

In mammalian systems (where the DNA polymerase does not have a 5'- 3' exonuclease

activity), Okazaki fragments are connected by a two-step process. Synthesis of an Okazaki fragment displaces the RNA primer of the preceding fragment in the form of a "flap’’.

The base of the flap is cleaved by the enzyme FEN1 (flap endonuclease 1 ) .

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#Id: 10229

#Unit 6. System Physiology – Plant