Simultaneously, two serines in each Smad2/3 phosphorylated by RI receptor kinase bind to phosphoserine-binding sites in the MH2 domains of a Smad4

TLS Online TPP Program

#Id: 1006

#Unit 5. Developmental Biology

Ligand for Toll receptor protein- Spätzle protein

TLS Online TPP Program

#Id: 1007

#Unit 5. Developmental Biology

The dorsoventral patterning of the early Drosophila embryo is controlled by a regulatory protein called Dorsal.

TLS Online TPP Program

#Id: 1008

#Unit 5. Developmental Biology

Cytoplasmic inhibitor protein of dorsal is Cactus.

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#Id: 1009

#Unit 5. Developmental Biology

Mammalian sex determination is governed by the gonad-forming genes and by the hormones elaborated by the gonads.

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#Id: 1010

#Unit 5. Developmental Biology

In mammals, the conversion of the genital ridge into the bipotential gonad requires, among others, the Sf1, Wt1, and Lhx9 genes.

TLS Online TPP Program

#Id: 1011

#Unit 5. Developmental Biology

In mammals, the bipotential gonad appears to be moved into the female pathway (ovary development) by the Foxl2, Wnt4, and Rspo1 genes.