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#Unit 4. Cell Communication and Cell Signaling #TGF-β Signaling #Part B Pointers
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TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Bacterial Infections
Bacteria enter the body through several natural routes.

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Cell wall endotoxins of some gram-negative bacteria activate macrophages, resulting in release of high levels of IL-1 and TNF-α, which can cause septic shock.

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#Unit 4. Cell Communication and Cell Signaling

In staphylococcal food poisoning and toxic shock syndrome, exotoxins produced by the pathogens function as superantigens, which can activate all T cells. 

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#Unit 4. Cell Communication and Cell Signaling

Extracellular Bacteria

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Intracellular bacterial
Intracellular bacterial infections tend to induce a cell-mediated immune response, specifically DTH. 
In this response, cytokines secreted by CD4+ T cells are important—most notably IFN-ϒ, which activates macrophages.

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