TLS Online TPP Program

#Id: 938


Induced pluripotent stem cell (iPSC) with the pluripotency of an embryonic stem cell. These genes were 
a. Sox2 and Oct4 (Oct3, Oct3/4, and Pou5f1) -which activated Nanog and other transcription factors that   established pluripotency and blocked differentiation
b. c-Myc which opened up chromatin and made the genes accessible to Sox2, Oct4, and Nanog
c. Klf4 -which prevents cell death

#Unit 5. Developmental Biology #Stem cells #Part B Pointers