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Ligand binding triggers a conformational change in the JAKs & they phosphorylate each other on a critical tyrosine in the activation loop which greatly enhances kinase activity

#Unit 4. Cell Communication and Cell Signaling #Cytokine Receptors & JAK/STAT Signaling Pathway #Part B Pointers
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#Unit 4. Cell Communication and Cell Signaling

Myosin II
Two heads and assembles into bipolar filaments
Small and non-processive
Function- Contraction 

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#Id: 9285

#Unit 6. System Physiology – Plant

O2‐sensitive hemoprotein kinase FixL controls a regulatory cascade that activates transcription of nitrogen fixation genes

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#Id: 888

#Unit 13. Methods in Biology

The repeat region of the Huntington disease locus (HD) in six individuals is amplified by PCR and analyzed by gel electrophoresis as shown in the following figure; the numbers to the right indicate the sizes of the PCR products in bp.

               

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#Id: 4649

#Unit 13. Methods in Biology

bromodeoxyuridine (BrdU) is rapidly phosphorylated and incorporated in its place into newly synthesized DNA hence BrdU is used to detect replicating cells



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#Id: 5055

#Unit 3. Fundamental Processes

DnaA then acts at three A-T–rich 13-bp tandem repeats located on the left side of oriC.


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