Nurturing Life Sciences
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#Unit 3. Fundamental Processes
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Bacterial promoters
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The consensus sequence reflects preferred –10 and –35 regions, separated by the optimum spacing (17 bp).
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Promoters with sequences closer to the consensus are generally “stronger” than those that match less well
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consensus sequence of TATAAT in which the leading TA and the final T are highly conserved. Upstream sequences around position –35 also have a region of sequence similarity, TTGACA.
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