Fast block to polyspermy 

Within 1–3 seconds after the binding of the first sperm, the membrane potential shifts from -70mV to about +20 mV

TLS Online TPP Program

#Id: 7374

#Unit 5. Developmental Biology

Gurken protein is a member of the EGF (epidermal growth factor) family, and Torpedo encodes a homologue of the vertebrate EGF receptor.

TLS Online TPP Program

#Id: 7375

#Unit 5. Developmental Biology

When Gurken binds to Torpedo, the terminal follicle cells differentiate into posterior follicle cells and synthesize a molecule that activates protein kinase A in the egg.

TLS Online TPP Program

#Id: 7376

#Unit 5. Developmental Biology

Par-1 protein organizes microtubules specifically with their minus and plus ends at the anterior and posterior ends of the oocyte, respectively

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#Id: 7377

#Unit 5. Developmental Biology

Bicoid mRNA binds to dynein, a “minus-directed” motor protein associated with the nongrowing end of microtubules; dynein moves the bicoid mRNA to the anterior end of the egg. 

TLS Online TPP Program

#Id: 7378

#Unit 5. Developmental Biology

Par-1 protein organizes microtubules specifically with their minus and plus ends at the anterior and posterior ends of the oocyte, respectively

TLS Online TPP Program

#Id: 7379

#Unit 5. Developmental Biology

Bicoid mRNA binds to dynein, a “minus-directed” motor protein associated with the nongrowing end of microtubules; dynein moves the bicoid mRNA to the anterior end of the egg.