In resting state,  the activation loop is not phosphorylated and assumes a conformation that blocks kinase activity.

In insulin receptor, it prevents binding of ATP. 

In FGF receptor, it prevents binding of substrate.

TLS Online TPP Program

#Id: 6394

#Unit 2. Cellular Organization

Major enzyme is Tryptophan Synthase

TLS Online TPP Program

#Id: 7229

#Unit 5. Developmental Biology

Lineage commitment

TLS Online TPP Program

#Id: 4482

#Unit 13. Methods in Biology

Eosin binds to acidic molecules (DNA and side chains of aspartate and glutamate).

TLS Online TPP Program

#Id: 8078

#Unit 13. Methods in Biology

TLS Online TPP Program

#Id: 1419

#Unit 4. Cell Communication and Cell Signaling

An integrin molecule is composed of two noncovalently associated transmembrane glycoprotein subunits called α and β.