For most, but not all, RTKs, the weakly active kinase in each subunit is phosphorylate a key tyrosine in the activation loop of the other subunit (trans-phosphorylation)

TLS Online TPP Program

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#Unit 11. Evolution and Behavior

There are three basic modes of selection on a quantitative trait.

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#Unit 11. Evolution and Behavior

Overdominance, the heterozygote has higher fitness than the  fitness of the two homozygotes.

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#Unit 11. Evolution and Behavior

Underdominance, in which the heterozygote has lower fitness than both homozygotes.

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#Unit 11. Evolution and Behavior

Directional selection leads to fixation of the favored allele and elimination of the other allele.

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#Unit 11. Evolution and Behavior

Directional selection favors individuals at one extreme of a phenotypic distribution that have greater reproductive success in a particular environment.

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#Unit 11. Evolution and Behavior

Balance natural selection- Each morph has selective advantage with equal intensity.