Phosphorylation leads to a conformational change in the activation loop that unblocks kinase active site by reducing the Kd for ATP or the substrate to be phosphorylated.

TLS Online TPP Program

#Id: 7839

#Unit 1. Molecules and their Interaction Relevant to Biology

TLS Online TPP Program

#Id: 7840

#Unit 1. Molecules and their Interaction Relevant to Biology

Stereoisomers that are mirror images of each other are called enantiomers

TLS Online TPP Program

#Id: 7841

#Unit 1. Molecules and their Interaction Relevant to Biology

Isomers that have opposite configurations at one or more of the chiral centers but that are not mirror images of each other are called diastereomers

TLS Online TPP Program

#Id: 7842

#Unit 1. Molecules and their Interaction Relevant to Biology

Two sugars that differ in configuration at only one chiral center are described as epimers.

TLS Online TPP Program

#Id: 7843

#Unit 1. Molecules and their Interaction Relevant to Biology

d-mannose and d-talose are epimers and d-glucose and d-mannose are epimers, whereas d-glucose and d-talose are not epimers but merely diastereomers

TLS Online TPP Program

#Id: 7844

#Unit 1. Molecules and their Interaction Relevant to Biology

Linear form of glucose (and other aldohexoses) could undergo a intramolecular reaction to form a cyclic hemiacetal.