In conditional specification the array of interactions it has with its neighbors, which may include: 

cell-to-cell contacts (juxtacrine factors)

secreted signals (paracrine factors)

physical properties of its local environment (mechanical stress)

TLS Online TPP Program

#Id: 3661

#Unit 3. Fundamental Processes

The gene can be restored to normal function if a second mutation either (1)converts the misplaced termination codon to a codon specifying an amino acid or (2) suppresses the effects of the termination codon, such restorative mutations are called nonsense suppressors.

TLS Online TPP Program

#Id: 3662

#Unit 3. Fundamental Processes

Pyl is specified by the codon UAG (normally a Stop codon).

TLS Online TPP Program

#Id: 3663

#Unit 3. Fundamental Processes

The Wobble Base of the Anticodon Determines the Number of Codons a tRNA Can Recognize.

TLS Online TPP Program

#Id: 3664

#Unit 3. Fundamental Processes

Ribosomes are large ribonucleoprotein particles that contain more RNA than protein and dissociate into large and small subunits.

TLS Online TPP Program

#Id: 3665

#Unit 3. Fundamental Processes

Size comparisons show that the ribosome is large enough to bind tRNAs and mRNA.

TLS Online TPP Program

#Id: 3666

#Unit 3. Fundamental Processes

Aminoacyl-tRNA Formation Is Very Accurate, the frequency of mischarging is very low; typically, less than 1 in 1000 tRNAs is charged with the incorrect amino acid.