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CONSTITUTIVE PHOTOMORPHOGENESIS1 (COP1), another negative regulator of photomorphogenesis, is a component of the E3 ubiquitin ligase complex that targets photomorphogenesis-promoting proteins for degradation such as phyA, phyB.

#Unit 6. System Physiology – Plant #Mechanisms of action of Phytochromes #Part B Pointers
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#Unit 4. Cell Communication and Cell Signaling

SOCS-1, binds to the critical phosphotyrosine in the activation loop of an activated JAK2 kinase, inhibiting its catalytic activity

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling


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#Unit 4. Cell Communication and Cell Signaling


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#Unit 4. Cell Communication and Cell Signaling

NGF, PDGF, FGF, EGF, insulin are RTK ligands, which trigger proliferation of cells.

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#Unit 4. Cell Communication and Cell Signaling

The cytosolic domain of RTKs contains an intrinsic protein tyrosine kinase domain.

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#Unit 4. Cell Communication and Cell Signaling

Cytosolic kinase domain of an RTK contains a flexible domain termed activation loop. 

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