Pattern recognition receptors (PRRs)

Receptors of the innate immune system that recognize molecular patterns or motifs present on pathogens but absent in the host.

TLS Online TPP Program

#Id: 7401

#Unit 5. Developmental Biology

Cleaved Easter binds to and cleaves Spätzle; activated Spätzle binds to Toll receptor protein

TLS Online TPP Program

#Id: 7402

#Unit 5. Developmental Biology

Toll activation activates Tube and Pelle, which phosphorylate the Cactus protein. Cactus is degraded, releasing it from Dorsal.

TLS Online TPP Program

#Id: 7403

#Unit 5. Developmental Biology

Cytoplasmic inhibitor protein of dorsal is Cactus.

TLS Online TPP Program

#Id: 7404

#Unit 5. Developmental Biology

Dorsal protein enters the nucleus and ventralizes the cell

TLS Online TPP Program

#Id: 7405

#Unit 5. Developmental Biology

Dorsal protein is a transcription factor that activates the genes that generate the ventrum.

TLS Online TPP Program

#Id: 7406

#Unit 5. Developmental Biology

The highest concentrations of Dorsal in the most ventral cell nuclei, become the mesoderm