Eventually some of the merozoites differentiate into male and female gametocytes, which are ingested by a mosquito and differentiate into gametes in the mosquito’s gut. 

TLS Online TPP Program

#Id: 6445

#Unit 8. Inheritance Biology

To obtain a lod score, we calculate 

the probability of obtaining the observed results under the assumption that the genes are linked with a specified degree of recombination

the probability of obtaining the observed results under the assumption of independent assortment.

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#Id: 6446

#Unit 8. Inheritance Biology

TLS Online TPP Program

#Id: 6447

#Unit 8. Inheritance Biology

Suppose recombination frequency is 0.1, and that the probability of obtaining the same observations under the assumption of independent assortment is 0.0001. 

TLS Online TPP Program

#Id: 6448

#Unit 8. Inheritance Biology

A lod score of 3 or higher is usually considered convincing evidence for linkage.

A lod score of -2 or lower is usually considered convincing evidence for independent assortment.

TLS Online TPP Program

#Id: 6449

#Unit 8. Inheritance Biology

TLS Online TPP Program

#Id: 6450

#Unit 8. Inheritance Biology

A Lod score of 3 represents a Recombination Frequency (RF) that is 

3 times as likely as the hypothesis of no linkage. 

30 times as likely as the hypothesis of no linkage. 

100 times as likely as the hypothesis of no linkage. 

I000 times as likely as the hypothesis of no linkage.