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Formation of the Wnt/Fz/LRP complex at the cell
surface causes the adaptor protein Dishevelled, to bind to Fz and Axin to bind to LRP, resulting destabilization and inactivation of the destruction complex

#Unit 4. Cell Communication and Cell Signaling #Wnt Signaling #Part B Pointers
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TLS Online TPP Program

#Id: 4741

#Unit 5. Developmental Biology

The decision of the anterior and posterior axis depends on the position of the sperm pronucleus in egg.


TLS Online TPP Program

#Id: 4742

#Unit 5. Developmental Biology

C. elegans oocyte use the “partitioning-defective,” or PAR proteins, in establishing cell polarity. 


TLS Online TPP Program

#Id: 4743

#Unit 5. Developmental Biology

Cortical cytoplasm contains PAR-3, PAR-6 & PKC-3 Internal cytoplasm contains PAR-2 and PAR-1

TLS Online TPP Program

#Id: 4744

#Unit 5. Developmental Biology


TLS Online TPP Program

#Id: 4745

#Unit 5. Developmental Biology

PKC-3 restricts PAR-1 and PAR-2 to the internal cytoplasm by phosphorylating them.

TLS Online TPP Program

#Id: 4746

#Unit 5. Developmental Biology

Sperm microtubules contacts the cortical cytoplasm and initiates cytoplasmic movements that push the male pronucleus to the nearest end of the oblong oocyte.


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