TLS Online TPP Program

#Question id: 1430


2-hydroxyglutarate is produced in cancer cells:

#Biochemistry
  1. because cancer cells exhibit increased aerobic glycolysis.

  2. that have mutations in isocitrate dehydrogenase.

  3. to counteract all the lactate produced by aerobic glycolysis.

  4. that have mutations in alpha-ketoglutarate dehydrogense.

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TLS Online TPP Program

#Question id: 1399

#Life Sciences

Loss-of-function mutations in which of the following genes typifies colorectal carcinomas?

a. myc              b. K-ras                       c. p53              d. APC

TLS Online TPP Program

#Question id: 1400

#Biochemistry

Which property is shared by malignant tumor cells and transformed cells in culture?

a. reduced growth factor requirement                        b. attachment-dependent growth

c. loss of actin microfilaments                                    d. altered morphology

TLS Online TPP Program

#Question id: 1400

#Life Sciences

Which property is shared by malignant tumor cells and transformed cells in culture?

a. reduced growth factor requirement                        b. attachment-dependent growth

c. loss of actin microfilaments                                    d. altered morphology

TLS Online TPP Program

#Question id: 1401

#Biochemistry

Which of the following are proto-oncogenes?

a. fos               b. myc             c. p53              d. ras               e. Rb

TLS Online TPP Program

#Question id: 1401

#Life Sciences

Which of the following are proto-oncogenes?

a. fos               b. myc             c. p53              d. ras               e. Rb

TLS Online TPP Program

#Question id: 1402

#Biochemistry

Which of the following oncoproteins possess(es) protein kinase activity?