A mutation in the gene that codes for p53 can result in-

A. loss of an inhibitor protein, p21.

B. loss of a transcription factor.

C. uncontrolled cell growth and cancer.

Which of the following is correct?

#Question id: 1399

#Life Sciences

Loss-of-function mutations in which of the following genes typifies colorectal carcinomas?

a. myc              b. K-ras                       c. p53              d. APC

#Question id: 1400

#Biochemistry

Which property is shared by malignant tumor cells and transformed cells in culture?

a. reduced growth factor requirement                        b. attachment-dependent growth

c. loss of actin microfilaments                                    d. altered morphology

#Question id: 1400

#Life Sciences

Which property is shared by malignant tumor cells and transformed cells in culture?

a. reduced growth factor requirement                        b. attachment-dependent growth

c. loss of actin microfilaments                                    d. altered morphology

#Question id: 1401

#Biochemistry

Which of the following are proto-oncogenes?

a. fos               b. myc             c. p53              d. ras               e. Rb

#Question id: 1401

#Life Sciences

Which of the following are proto-oncogenes?

a. fos               b. myc             c. p53              d. ras               e. Rb

#Question id: 1402

#Biochemistry

Which of the following oncoproteins possess(es) protein kinase activity?