#Question id: 40417
#Applied Microbiology
Consider the following statements regarding ATP production during aerobic respiration:
Substrate-level phosphorylation occurs in both the cytoplasm and the mitochondrial matrix.
The oxidation of one molecule of Acetyl-CoA in the Citric Acid Cycle results in 11 ATPs via oxidative phosphorylation.
The enzyme ATP Synthase (Complex V) utilizes the proton motive force to generate ATP in the intermembrane space.
#Question id: 40418
#Applied Microbiology
Assertion (A) : The net gain of ATP during glycolysis is only 2 ATP, even though 4 ATP molecules are actually produced.
Reason (R): Two molecules of ATP are consumed during the preparatory phase of glycolysis to phosphorylate glucose and fructose-6-phosphate.
#Question id: 40419
#Applied Microbiology
Match the metabolic stage (Column I) with the correct ATP/Reduced Coenzyme yield per glucose molecule (Column II).
| Column I (Metabolic Stage) | Column II (Yield per Glucose) |
|---|---|
| P. Glycolysis (Net) | 1. 2 GTP + 6 NADH + 2 FADH₂ |
| Q. Pyruvate Decarboxylation | 2. 2 ATP + 2 NADH |
| R. Citric Acid Cycle | 3. 2 NADH + 2 CO₂ |
#Question id: 40420
#Applied Microbiology
A point mutation occurs in a DNA sequence, changing the codon UAC (Tyrosine) to UAA (Stop). This specific type of mutation is classified as:
#Question id: 40421
#Applied Microbiology
Consider the following statements regarding mutations:
A silent mutation is a change in the DNA sequence that does not change the amino acid sequence of the protein.
Missense mutations always result in the complete loss of protein function.
Frameshift mutations typically occur due to the insertion or deletion of nucleotides in numbers not divisible by three.
#Question id: 40422
#Applied Microbiology
Assertion (A): Sickle cell anemia is a classic example of a missense mutation.
Reason (R): In the beta-globin chain of hemoglobin, a single nucleotide substitution results in the replacement of Glutamic acid by Valine at the sixth position