TLS Online TPP Program

#Question id: 53


Calculate the number of times the DNA of a modern E. coli cell has been copied accurately since its earliest bacterial precursor cell arose about 3.5 billion years ago. Assume for simplicity that over this time period, E. coli has undergone, on average, one cell division every 12 hours (this is an overestimate for modern bacteria, but probably an underestimate for ancient bacteria).

#Section C (Domain-Specific Knowledge)
  1. 4.6 × 10^12 generations

  2. 3.4 × 10^13 generations

  3. 2.6 × 10^12 generations

  4. 2.6 × 10^11 generations

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TLS Online TPP Program

#Question id: 27068

#Section C (Domain-Specific Knowledge)

Isoleucine and Threonine have two chiral carbons so exists in multiple RS configuration, choose the correct option regarding the given fig.
1. a is D-threonine is (2S, 3S) threonine
2. b is L-threonine is (2R,3S) threonine
3. a is L-threonine is (2S, 3R) threonine
4. b is D-threonine is (2R,3S) threonine

TLS Online TPP Program

#Question id: 27069

#Section C (Domain-Specific Knowledge)

Choose the correct option regarding the stereochemistry of given compound 

TLS Online TPP Program

#Question id: 27070

#Section C (Domain-Specific Knowledge)

Which of the following statements is correct regarding the stereochemistry of Thr, Ile 
1. Thr, Ile is special case because of two chiral center exist in L-Ile in 2R,3S and L-Thr in 2R,3S configuration 
2. Thr, Ile is special case because of two chiral center exist in D-Ile in 2R,3S and D-Thr in 2R,3S configuration 
3. Thr, Ile is special case because of two chiral center exist in L–Ile in 2S,3R and L–Thr in 2S,3R 
4. Thr, Ile is special case because of two chiral center exist in D–Ile in 2S,3R and D–Thr in 2S,3R

TLS Online TPP Program

#Question id: 1232

#Section C (Domain-Specific Knowledge)

Which of the following mutations might confer a competitive advantage to an athlete by raising his or her hematocrit?

a. excess production of erythropoietin                       

b. decreased production of erythropoietin

c. EpoR that cannot bind STAT5                  

d. EpoR that cannot bind SHP1

e. EpoR that cannot bind JAK2

TLS Online TPP Program

#Question id: 88

#Section C (Domain-Specific Knowledge)

Anomers can be interconverted ________.

TLS Online TPP Program

#Question id: 27159

#Section C (Domain-Specific Knowledge)

This event can cause a damage to the hypothalamus portal system