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#Section 2: General Biology #T cells #Part B Pointers
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#Section 3: Genetics, Cellular and Molecular Biology

The Golgi consists of four functionally distinct regions:

a. Cis compartments

b. Medial compartments

c. Trans compartments

d. Trans-Golgi network

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#Section 3: Genetics, Cellular and Molecular Biology

Catastrophe 
The change from growth to shrinkage

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#Section 3: Genetics, Cellular and Molecular Biology

Most common CFTR mutation is a ΔF508 -
Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 
Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.

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#Section 3: Genetics, Cellular and Molecular Biology

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#Section 3: Genetics, Cellular and Molecular Biology

Defects of cohesin’s gene expression regulation function are the cause of a group of diseases collectively called cohesinopathies.

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