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TLS Online TPP Program

#Id: 10300

T-Cell Activation and Differentiation

#Section 2: General Biology #T cells #Part B Pointers
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TLS Online TPP Program

#Id: 8523

#Section 3: Genetics, Cellular and Molecular Biology
TLS Online TPP Program

#Id: 8522

#Section 3: Genetics, Cellular and Molecular Biology

Lysine acetylation 
ε-amino group of a specific lysine of α-tubulin
Microtubules are stabilized against breakage (centrioles, basal bodies, & primary cilia)
TLS Online TPP Program

#Id: 8521

#Section 3: Genetics, Cellular and Molecular Biology

Lysine acetylation & Detyrosylation are found only on α-tubulin and are absent from β-tubulin.
TLS Online TPP Program

#Id: 8520

#Section 3: Genetics, Cellular and Molecular Biology

Post-translational modifications of tubulin:
Lysine acetylation
Detyrosylation
Polyglutamylation
Polyglycylation
TLS Online TPP Program

#Id: 8519

#Section 3: Genetics, Cellular and Molecular Biology
TLS Online TPP Program

#Id: 8518

#Section 3: Genetics, Cellular and Molecular Biology

Defects in LIS1 
Miller-Dieker lissencephaly
means “smooth brain”