The idea behind CARs was to engineer the T-cell receptor to trigger activation of ZAP70 in response to the presence of a tumor-specific antigen rather than the MHC peptide complex. 

TLS Online TPP Program

#Id: 10379

#Section 2: General Biology

TLS Online TPP Program

#Id: 8858

#Section 3: Genetics, Cellular and Molecular Biology

Cohesin-mediated cohesion between sister chromatids is established by a two-step process:

1.Loading and unloading of cohesins

2. Stabilization of cohesins

TLS Online TPP Program

#Id: 9268

#Section 2: General Biology

Nitrogenase is a complex consisting of the MoFe protein (dinitrogenase or component I) a heterotetramer, and the Fe protein (dinitrogenase reductase or component II) a homodimer.

TLS Online TPP Program

#Id: 8397

#Section 3: Genetics, Cellular and Molecular Biology

Z disk 

Thin actin filaments are assembled with their (+) ends embedded in a densely staining structure

TLS Online TPP Program

#Id: 3781

#Section 2: General Biology

The multi-atom combinations are called molecules. A molecule is the smallest part of a substance that has the physical and chemical properties of that substance.