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TLS Online TPP Program

#Id: 10381

IL-4 increases expression of class II molecules in resting B cells, turning them into more efficient APCs.

#Section 2: General Biology #Major histocompatibility complex #Part B Pointers
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TLS Online TPP Program

#Id: 8338

#Section 3: Genetics, Cellular and Molecular Biology

Profilin can bind proteins with sequences rich in proline residues at the same time it is bound to actin.
TLS Online TPP Program

#Id: 8337

#Section 3: Genetics, Cellular and Molecular Biology

Profilin – G-actin nucleotide exchange (ADP to ATP) 
Cofilin – F-actin disassembly
Thymosin B-4 – G-actin monomer sequestering
TLS Online TPP Program

#Id: 8336

#Section 3: Genetics, Cellular and Molecular Biology

Actin filament treadmilling is accelerated by:

Profilin and Cofilin
TLS Online TPP Program

#Id: 8335

#Section 3: Genetics, Cellular and Molecular Biology
TLS Online TPP Program

#Id: 8334

#Section 3: Genetics, Cellular and Molecular Biology

Phalloidin 
isolated from Amanita phalloides, binds at the interface between subunits in F-actin, locking adjacent subunits together and preventing depolymerization.
TLS Online TPP Program

#Id: 8333

#Section 3: Genetics, Cellular and Molecular Biology

Jasplakinolide,
a sponge toxin, enhances nucleation by binding and stabilizing actin dimers and lowering the Cc.