The SRP and the nascent polypeptide chain–ribosome complex bind to the SRP receptor in the ER membrane. This interaction is strengthened by the binding of GTP to both the SRP and its receptor.

TLS Online TPP Program

#Id: 8147

#Section 3: Genetics, Cellular and Molecular Biology

A clathrin molecule,

called a triskelion, is composed of : 

Three heavy chains

Three light chains

TLS Online TPP Program

#Id: 8146

#Section 3: Genetics, Cellular and Molecular Biology

TLS Online TPP Program

#Id: 8145

#Section 3: Genetics, Cellular and Molecular Biology

Vesicle Type- Clathrin

Transport - trans-Golgi to endosome

Coat Proteins – Clathrin + AP1 complexes

                            Clathrin + GGA

Associated GTPase- ARF

TLS Online TPP Program

#Id: 8144

#Section 3: Genetics, Cellular and Molecular Biology

Vesicle Type- COPI

Transport - cis-Golgi to ER

Coat Proteins – Coatomers

Associated GTPase- ARF

TLS Online TPP Program

#Id: 8143

#Section 3: Genetics, Cellular and Molecular Biology

Vesicle Type- COPII

Transport - ER to cis-Golgi 

Coat Proteins - Sec23/Sec24 and Sec13/Sec31, Sec16

Associated GTPase- Sar1

TLS Online TPP Program

#Id: 8142

#Section 3: Genetics, Cellular and Molecular Biology

Retrograde transport

COPI vesicles = cis-Golgi to ER