Nurturing Life Sciences
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Saturation = extent of packing
Fully saturated fatty acids in the extended form pack into nearly crystalline arrays, stabilized by many hydrophobic interactions.
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#Section 3: Genetics, Cellular and Molecular Biology
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formin family members have two adjacent domains:
FH1- rich in proline, landing site for profilin–ATP–G-actin
FH2 - form a dimer and nucleate filament assembly
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#Section 2: General Biology
The idea behind CARs was to engineer the T-cell receptor to trigger activation of ZAP70 in response to the presence of a tumor-specific antigen rather than the MHC peptide complex.
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