TLS Online TPP Program

#Id: 8328

#Section 3: Genetics, Cellular and Molecular Biology

Hydrolysis of the bound nucleotide reduces the binding affinity of the subunit for neighbouring subunits and makes it more likely to dissociate from each end of the filament.

T form that adds to the filament and the D form that leaves.

TLS Online TPP Program

#Id: 8131

#Section 2: General Biology

In most mammalian tissues, ubiquinone (also called coenzyme Q) has 10 isoprene units.

Dolichols of animals have 17 to 21 isoprene units (85 to 105 carbon atoms), bacterial dolichols have 11, and those of plants and fungi have 14 to 24.

TLS Online TPP Program

#Id: 8197

#Section 3: Genetics, Cellular and Molecular Biology

Zellweger syndrome

Autosomal recessive Mutations in any of a dozen different peroxins, the most common being Pex1, cause an impairment in peroxisomal protein import.

TLS Online TPP Program

#Id: 10324

#Section 2: General Biology

PD-1 has a structure similar to CTLA-4 and when activated negatively regulates T-cell function by inducing apoptosis of activated T cells. 

TLS Online TPP Program

#Id: 8415

#Section 3: Genetics, Cellular and Molecular Biology

Dilated cardiomyopathy

Minor missense mutations in the cardiac actin gene