Excreted S1P provokes many different cell and tissue effects, among them inflammation in allergic reactions, cell proliferation, angiogenesis, malignant transformation, and movement and migration of certain cells.

TLS Online TPP Program

#Id: 9161

#Section 3: Genetics, Cellular and Molecular Biology

Close inbreeding is harmful because it increases the proportion of homozygotes and thereby boosts the probability that deleterious and lethal recessive alleles.

TLS Online TPP Program

#Id: 10302

#Section 2: General Biology

Positive Costimulatory Receptors: ICOS

ICOS binds to another member of the growing B7 family, ICOS-ligand (ICOS-L), which is also expressed on a subset of activated APCs.

ICOS plays a key role in maintaining the activity of already differentiated effector and memory T cells.

TLS Online TPP Program

#Id: 8613

#Section 3: Genetics, Cellular and Molecular Biology

Threonine -160 phosphorylation is mediated by 

CDK-activating kinase (CAK)

TLS Online TPP Program

#Id: 8410

#Section 3: Genetics, Cellular and Molecular Biology

TN-C is the calcium-binding subunit, controls the

position of TM on the surface of an actin filament through the TN-I and TN-T subunits

TLS Online TPP Program

#Id: 8539

#Section 3: Genetics, Cellular and Molecular Biology

The short (∼20 amino acid) C-terminal tails of both α- and β-tubulin that protrude from the microtubule are enriched in glutamic and aspartic acids, the surface of the microtubule possesses a net negative charge.