Autophagy occurs in the following sequence of steps:

Induction by activation of mTOR complex 1

• Nucleation of autophagosome formation by ATG9

• Closure of the membrane cup to form autophagosome

• Fusion of the autophagosome with lysosomes, catalyzed by SNAREs.

• Digestion of the inner membrane and the lumenal contents of the autophagosome

TLS Online TPP Program

#Id: 8634

#Section 3: Genetics, Cellular and Molecular Biology

At the metaphase to anaphase transition, APC/C bound to Cdc20 targets cyclins A /B and securin for degradation.

TLS Online TPP Program

#Id: 8605

#Section 3: Genetics, Cellular and Molecular Biology

S phase Cyclin–CDKs

In human - cyclin A-CDK 2 

In budding yeast - CIb 5/6-Cdc 28

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#Id: 8169

#Section 3: Genetics, Cellular and Molecular Biology

Rab·GTP is enabled to bind to a variety of different proteins, known as Rab effectors.

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#Id: 8639

#Section 3: Genetics, Cellular and Molecular Biology

Phosphorylation of Whi5 promotes its export out of the nucleus, allowing the transcription factor complex SBF to induce transcription of the G1/S phase cyclin genes CLN1 and CLN2.

TLS Online TPP Program

#Id: 7936

#Section 3: Genetics, Cellular and Molecular Biology

The SRP is made up of six proteins bound to a 300-nucleotide RNA, which acts as a scaffold for the hexamer.