Nucleation phase 

Two G-actin molecules bind relatively weakly to each other, but addition of a third actin monomer to form a trimer makes the entire group more stable, acts as a nucleus for polymerization.

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#Id: 10326

#Section 2: General Biology

Antibodies against 

CTLA-4

PD-L1 or PD-1

A CTLA-4-blocking antibody, ipilimumab

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#Id: 8171

#Section 3: Genetics, Cellular and Molecular Biology

In mammalian cells, Rab5 protein (early endosomes) and its effector protein known as EEA1 (early endosome antigen 1)

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#Id: 8339

#Section 3: Genetics, Cellular and Molecular Biology

Filament capping proteins:

CapZ blocks (+)end Tropomodulin blocks (-)end

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#Id: 8631

#Section 3: Genetics, Cellular and Molecular Biology

APC/C core is organized into three modules: 

1. a scaffold module 

2. a catalytic module

3. a substrate recognition module

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#Id: 9273

#Section 2: General Biology