In vertebrate smooth muscle, phosphorylation of the myosin regulatory light chain activates contraction in Ca2+ dependent manner.

TLS Online TPP Program

#Id: 8366

#Section 3: Genetics, Cellular and Molecular Biology

Myosin I

single head domain

Function- Membrane association, endocytosis

TLS Online TPP Program

#Id: 8093

#Section 2: General Biology

TLS Online TPP Program

#Id: 8167

#Section 3: Genetics, Cellular and Molecular Biology

Most common CFTR mutation is a ΔF508 -

Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 

Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.

TLS Online TPP Program

#Id: 9263

#Section 2: General Biology

Anammox is anaerobic production of molecular nitrogen from NH4 +and NO2–

TLS Online TPP Program

#Id: 7952

#Section 3: Genetics, Cellular and Molecular Biology

Two N- acetylglucosamine (GlcNAc) and five mannose residues are added one at a time to a dolichol phosphate on the cytosolic face of the ER membrane