INK4s

bind to CDK4 and CDK6 monomers, blocking their interaction with cyclin D

TLS Online TPP Program

#Id: 8099

#Section 2: General Biology

TLS Online TPP Program

#Id: 8965

#Section 3: Genetics, Cellular and Molecular Biology

Most protein-encoding genes, the synonymous rate of change is considerably higher than the nonsynonymous rate because synonymous mutations are tolerated by natural selection

TLS Online TPP Program

#Id: 7941

#Section 3: Genetics, Cellular and Molecular Biology

The translocon was first identified through mutations in the yeast gene encoding a protein called Sec61α

TLS Online TPP Program

#Id: 9213

#Section 3: Genetics, Cellular and Molecular Biology

Probability of being heterozygote in given population

H = 1 - 1/2N

TLS Online TPP Program

#Id: 10362

#Section 2: General Biology

T-independent response

Type 1 T-independent (TI-1) antigens bind to B cells through both Ig and innate immune receptors. LPS from Gram negative organisms binds to B cells via both mIg and TLR, resulting in signaling from both receptors.