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The entire process of mitotic CDKs activation and entry into mitosis involves two positive feedback loops and coordination between events at the centrosome, in the cytoplasm, and in the nucleus.

#Section 3: Genetics, Cellular and Molecular Biology #Steps in cell cycle, regulation and control of cell cycle #Part B Pointers
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TLS Online TPP Program

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#Section 2: General Biology

T-cell lineage

TLS Online TPP Program

#Id: 10290

#Section 2: General Biology

T-Cell Development
1.Commitment
2.antigen receptor gene rearrangements
3.The selection and expansion of cells (β-selection

TLS Online TPP Program

#Id: 10291

#Section 2: General Biology

The second phase of T-cell development
1.Positive selection: Selection for those cells whose T-cell receptors engage self-MHC.
2.Negative selection: Selection against those cells whose T-cell receptors bind too strongly to self-peptide/MHC combinations.
3.Lineage commitment: Commitment of thymocytes to effector cell lineages, including CD4 helper or CD8 cytotoxic populations

TLS Online TPP Program

#Id: 10292

#Section 2: General Biology

TLS Online TPP Program

#Id: 10293

#Section 2: General Biology

TLS Online TPP Program

#Id: 10294

#Section 2: General Biology

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