Duplicate gene and its parental copy can subfunctionalize so that each carries out only some of the roles that the ancestral gene performed. 

Ex- a duplicate of the β-hemoglobin locus is expressed in the fetus. 

TLS Online TPP Program

#Id: 8601

#Section 3: Genetics, Cellular and Molecular Biology

TLS Online TPP Program

#Id: 8602

#Section 3: Genetics, Cellular and Molecular Biology

cyclin-CDK complexes preferentially phosphorylate

serine and threonine residues when they are found within the consensus sequence:

[S/T]PX[R/K]K 

TLS Online TPP Program

#Id: 8603

#Section 3: Genetics, Cellular and Molecular Biology

G1 Cyclin–CDKs

In human - cyclin D-CDK 4 

cyclin D-CDK 6

In budding yeast - CIn 3-Cdc 28 

TLS Online TPP Program

#Id: 8604

#Section 3: Genetics, Cellular and Molecular Biology

G1/S Cyclin–CDKs

In human - cyclin E-CDK 2 

In budding yeast - CIn 1/2-Cdc 28

TLS Online TPP Program

#Id: 8605

#Section 3: Genetics, Cellular and Molecular Biology

S phase Cyclin–CDKs

In human - cyclin A-CDK 2 

In budding yeast - CIb 5/6-Cdc 28

TLS Online TPP Program

#Id: 8606

#Section 3: Genetics, Cellular and Molecular Biology

M phase Cyclin–CDKs

In human - cyclin A-CDK 1

cyclin B-CDK 1

In budding yeast - CIb 1/2/3/4-Cdc 28