No matter how it is born, a new gene starts its life as a single copy in the population.

As with any new mutation, by far the most likely outcome is that it will be lost by random drift or selection over the next few generations

TLS Online TPP Program

#Id: 10388

#Section 2: General Biology

Class II presentation can occur with either live or replication-incompetent virus; protein synthesis inhibitors had no effect, indicating that new protein synthesis is not a necessary condition of class II presentation. 

TLS Online TPP Program

#Id: 10389

#Section 2: General Biology

Class II, but not class I, presentation is inhibited by treatment of the cells with an agent that blocks endocytic processing within the cell (chloroquine).

TLS Online TPP Program

#Id: 10286

#Section 2: General Biology

T cells initiate the adaptive immune response by interacting MHC on antigen-presenting cells that have been exposed to pathogens. 

TLS Online TPP Program

#Id: 10287

#Section 2: General Biology

T-Cell - Cells leaving the thymus are functional, mature T cells expressing unique and specific T-cell receptors (TCRs) that are both tolerant to self and restricted to self-MHC.

TLS Online TPP Program

#Id: 10288

#Section 2: General Biology

TLS Online TPP Program

#Id: 10289

#Section 2: General Biology

T-cell lineage