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#Section 3: Genetics, Cellular and Molecular Biology #Population Genetics #Part B Pointers
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#Section 3: Genetics, Cellular and Molecular Biology

During S phase
DNA-bound G1 cohesins Convert into cohesive complexes by cohesin acetyl transferases (CoATs)
which acetylate Smc3 subunit & prevents unloading of cohesins by Pds5-Wapl, thereby stabilizing the cohesins on chromosomes.

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M6P residues are generated in the cis-Golgi by two Golgi-resident enzymes. 
  1. N-acetylglucosamine (GlcNAc) phosphotransferase
  2. Phosphodiesterase

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Close inbreeding is harmful because it increases the proportion of homozygotes and thereby boosts the probability that deleterious and lethal recessive alleles.

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