Dissociation of cytosolic complex leads to the stabilization of the full-length Ci, which moves into the

nucleus, displaces the repressor Ci75 from the promoter of target genes, and induces expression of target genes.

TLS Online TPP Program

#Id: 9657

#XL - T Zoology

Negative feedback regulation by MAP Kinase

activated MAP kinase triggers an increase in the expression of dual-specificity phosphatases (DUSPs), particularly DUSP6.

TLS Online TPP Program

#Id: 8852

#XL - T Zoology

Geminin contains a destruction box at its N-terminus that is recognized by APC/Ccdh1, causing it to be ubiquitinylated in late anaphase and degraded by proteasomes.

TLS Online TPP Program

#Id: 8914

#XL - T Zoology

Following securin degradation and a decrease in mitotic CDK activity, separase cleaves the Scc1 subunit, breaking the cohesin circles.

TLS Online TPP Program

#Id: 8024

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 9207

#XL - T Zoology