Integrin exist in two conformations: 

Inactive, low-affinity, “bent” conformation  

Active, high-affinity, “extended” conformation

TLS Online TPP Program

#Id: 9092

#XL - T Zoology

Pertussis toxin, produced by Bordetella pertussis, catalyzes ADP-ribosylation of the  subunit of Gαi, preventing GDP-GTP exchange and blocking inhibition of adenylyl cyclase.

TLS Online TPP Program

#Id: 10085

#XL - T Zoology

I-domains also recognize CAMs on other cells, 

ICAMs, VCAMs and participate in cell-cell adhesion.

TLS Online TPP Program

#Id: 7832

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8093

#XL - T Zoology

TLS Online TPP Program

#Id: 9272

#XL - S Microbiology