Tumors that arise from exposure to mutagens, such as melanomas (UV light) and lung carcinomas (tobacco smoke) the number of mutations may be hundredfold greater than this. These altered proteins are known as neo-antigens

TLS Online TPP Program

#Id: 8949

#XL - T Zoology

TLS Online TPP Program

#Id: 1313

#XL - T Zoology

Two large classes of GTPase switch proteins-

Heterotrimeric G proteins

Monomeric G proteins

TLS Online TPP Program

#Id: 1314

#XL - T Zoology

GTP-binding switch proteins contains two domain-

Switch I- Thr-35

Switch II- Gly-60 

TLS Online TPP Program

#Id: 1315

#XL - T Zoology

GTPase superfamily of proteins- eIF2, EF1α, EF2, Ran, Sar, Rab, Rho, Rac, Cdc42

TLS Online TPP Program

#Id: 1316

#XL - T Zoology

G protein coupled receptor contains seven membrane-spanning α helices & heterotrimeric G protein.

TLS Online TPP Program

#Id: 1317

#XL - T Zoology

Muscarinic acetylcholine receptor is coupled to a Gαi protein.