Engineering T Cells to Recognize Tumor Antigens

When reactivated by inhibition of the immune checkpoint, have the capacity to recognize and kill some tumors with a large burden of mutations.

TLS Online TPP Program

#Id: 9071

#XL - T Zoology

Feedback mechanisms suppress signaling by the PKA pathway:

1. Intrinsic GTPase activity of Gαs

2. PDE acts to hydrolyze cAMP to 5′-AMP

3. By BARK

TLS Online TPP Program

#Id: 10747

#XL - R Botany

Simple cyme (solitary)

Determinate inflorescence consist of a single flower, it may be terminal or axillary

Example: Hibiscus rosa-sinensis

TLS Online TPP Program

#Id: 9970

#XL - T Zoology

In the absence of Wnts,

“free” β-catenin are targeted for degradation by a cytosolic destruction complex that is held together by the tumor suppressor protein Axin.

TLS Online TPP Program

#Id: 9679

#XL - T Zoology

The cytosolic phosphoserine binding protein 14-3-3 then binds to phosphorylated FOXO3a and sequesters it in the cytosol.

TLS Online TPP Program

#Id: 10713

#XL - R Botany

Feature of root

Most Vascular plants has two types of roots;

I. Primary Roots (Tap root) that grow downward

II. Secondary Roots that branch out to the side